Recycling of hard-core smokers with nicotine nasal spray

Recycling of hard-core smokers with nicotine nasal spray.

The primary aim of this smoking cessation study was to evaluate the effect of long-term treatment with nicotine nasal spray in a group of hard-core smokers. A further aim was to compare the effect of ad libitum with fixed dosage of nasal nicotine spray. Eighty nine smokers, failures from two earlier studies with nicotine patches, were enrolled in an open smoking cessation study with nicotine na...

Effects of nicotine patch or nasal spray on nicotine and cotinine concentrations in pregnant smokers.

OBJECTIVE To examine the short-term effects of the nicotine patch or nasal spray on measures of nicotine exposure, withdrawal symptoms, and on maternal and fetal heart rates in pregnant smokers. METHODS We measured nicotine/cotinine concentrations and maternal and fetal heart rates during an 8-h monitoring session while smoking and again after 4 days of nicotine patch (15 mg/16 h), nasal spra...

Review of Nicotine nasal spray neither effective nor well-tolerated by adolescent smokers

Nicotine nasal spray neither effective nor well-tolerated by adolescent smokers.

Nicotine nasal spray with nicotine patch for smoking cessation: randomised trial with six year follow up.

OBJECTIVE To evaluate the efficacy of using a nicotine patch for 5 months with a nicotine nasal spray for 1 year. DESIGN Placebo controlled, double blind trial. SETTING Reykjavik health centre. SUBJECTS 237 smokers aged 22-66 years living in or around Reykjavik. INTERVENTIONS Nicotine patch for 5 months with nicotine nasal spray for 1 year (n=118) or nicotine patch with placebo spray (n...